李世清，桂林理工大学化学与生物工程学院副教授，硕士生导师。2008-2012年于云南大学化学科学与工程学院化学专业学习（获学士学位），2012-2017年于四川大学化学学院有机化学专业学习（硕博连读，获博士学位，导师：高戈教授/游劲松教授），2017年6月起就职于桂林理工大学，2022.09-2023.06于南开大学访学（合作导师：赵东兵教授/卜显和院士）。主要研究方向为有机合成方法学（新试剂与新反应）、高价碘化学、多组分串联环化反应与过程跟踪、有机光电材料/药物分子设计与合成，在Chem. Sci., Chin. Chem. Lett., Org. Lett., Org. Chem. Front., Chem. Commun.等国际知名学术刊物上发表SCI收录论文20余篇，主持国家自然科学基金项目2项，广西自然科学基金项目3项，获中国发明专利授权3项。详细研究成果及论文见X-Mol课题组网站：

https://www.x-mol.com/groups/LI_Shiqing-GLUT/publications

一、教育背景：

2008/9-2012/6 云南大学化学科学与工程学院，化学，本科

2012/9-2014/6 四川大学，化学学院，有机化学，硕士（导师：高戈/游劲松教授）

2014/9-2017/6 四川大学，化学学院，有机化学，博士（导师：高戈/游劲松教授）

2017/6-2021/11 桂林理工大学，化学与生物工程学院，讲师

2022/9-2023/7 南开大学，化学学院，访问学者（合作导师：赵东兵教授/卜显和院士）

2021/11至今 桂林理工大学，化学与生物工程学院，副教授

二、主讲课程：

《有机化学》、《大学化学》、《普通化学》、《无机化学》

三、研究方向与招生：

研究方向：C-H键多功能化串联反应构筑有机功能分子、高价碘化学、有机光电材料和药物分子的设计与合成。（课题组主页：https://www.x-mol.com/groups/LI_Shiqing-GLUT）

招生：招收化学、化学工程与技术、材料与化工、生物与医药等专业一志愿以及调剂录取的硕士研究生，欢迎有机化学爱好者报考本课题组！也欢迎喜欢科研的本科生加入课题组！

联系方式：桂林理工大学雁山校区9栋504室，邮箱：LSQ030080@126.com

四、主持的科研项目：

（1）国家自然科学基金，地区基金项目，22261013，环状酸酐介导无痕策略促使无机肼转化成有机含氮氮双键化合物研究，2023.01-2026.12，33万。

（2）国家自然科学基金，青年基金项目，22001049，C-H活化/联导向基策略一步构筑（轴手性）联异喹啉衍生物及其金属螯合物的应用，2021.01-2023.12，24万。

（3）广西自然科学基金，青年基金项目，2020GXNSFBA297003，2021.01-2023.12，8万。

（4）广西自然科学基金联合资助培育项目，2018GXNSFAA294037，2019.01-2021.04，20万。

（5）广西科技基地和人才专项，AD19245095，2020.01-2022.12，10万，主持。

五、代表性成果（论文）

2024

[29] Peiyan Zhu, Yanyan Yang, Hui Li, Jinhua Wang, Shiqing Li*. Rh(III)-Catalyzed sequential ring-retentive/-opening [4 + 2] annulations of 2H-imidazoles towards full-color emissive imidazo[5,1-a]isoquinolinium salts and AIE-active non-symmetric 1,1′-biisoquinolines. Chinese Chemical Letters, 2024, 35, 109533.  (一区，Link)

[28] Yi Xiao, Xiya Zhang, Yuqin Wang, Kaida Li (本科生), Guixia Wang, Xiangfei Kong, Jinhua Wang*, Shiqing Li*. Sequential annulation of bidentate diamines for the modular access to N-fused/helical/spiro-carbazole scaffolds. Organic Chemistry Frontiers, 2024, 11, 401–406.  (一区，Link)

2023

[27] Shiqing Li,‡*, Shihai Lv,‡  Yanyan Yang,‡, Peiyan Zhu,a Dongbing Zhao,*  Ming-Hua Zeng*. Mechanistic insights into an NH4OAc-promoted imine dance in Rhcatalysed multicomponent double C-H annulations through an N-retention/exchange dual channel. Chemical Science, 2023, 14, 13446–13452. (‡Equal contribution) (一区，Link)

[26] Yanyan Yang, Rongrong Xie, Yiwen Wang, Peiyan Zhu, Jinhua Wang, Shiqing Li*. Efficient synthesis of benzo[c]cinnolines and azoarenes via dual C−N coupling of phthalhydrazide and trivalent halogen reagents. Organic Chemistry Frontiers, 2023, 10, 2701–2707. (一区，Link)

[25] Chaoying Wen, Yuqin Wang, Yanyan Yang, Ya-Nan Tian, Jinhua Wang, Shiqing Li*. Hydrazone-oxime Selectively Directed Redox-Neutral [4 + 2] Annulations Cascade with Alkynes and Iodonium Ylides to Build 1,1′-Biisoquinoline Mono‑N‑oxides. Organic Letters, 2023, 25, 2616–2621.  (一区，Link)

[24] Rongrong Xie,‖ Yi Xiao,‖ Yiwen Wang, Zhi-Wei Xu, Ning Tian, Shiqing Li*, Ming-Hua Zeng*. Hydrazine−Halogen Exchange Strategy Toward N=N-Containing Compounds and Process Tracking for Mechanistic Insight. Organic Letters, 2023, 14, 2415–2419. (‖Equal contribution) (一区，封面文章，Link) (Highlighted by Organic Chemistry Portal)

              

[23] Yiwen Wang, Ya-Nan Tian, Shiyan Ren (本科生), Ruijie Zhu (本科生), Bin Huang(本科生), Yanqiong Wen(本科生), Shiqing Li*. Metal-free homo-/cross-anion–cation coupling of cyclic diaryl λ3-bromanes. Organic Chemistry Frontiers, 2023, 10, 793–798. (一区，Link)

[22] Linfeng Zhang, Dong Chen, Chao Zhou, Yutong Yin, Guixia Wang, Qiping Zhu, Shiqing Li*, Xiangfei Kong*. Synthesis of evodiamine and its derivatives through a visiblelight-driven intramolecular C-N-cross-coupling reaction. Tetrahedron Lett., 2023, 1115, 154305.  

[21] Ya-Nan Tian, Shihai Lv, Lingyu Huang, Chaoying Wen, Yanyan Yang, Xiangfei Kong, Qiping Zhu*, Shiqing Li*, Experimental and computational studies on rhodium-catalyzed C4(5)aryl−H activation/annulations of imidazoles with alkynes: facile synthesis of six types of N-heterocycles. Organic Chemistry Frontiers, 2023, 10, 83−91. (一区，Link)

2022

[20] Shihai Lv, Ya-Nan. Tian, Yanyan Yang, Chaoying Wen, Shiqing Li*. Rh(III)-Catalyzed One-Pot Three-Component Diannulation of Benzils, Ammonium Acetate, and Alkynes to Build 1,1′-Biisoquinolines. Journal of Organic Chemistry, 2022, 87, 16019−16025. (二区，Link)

[19] Lingyu Huang, Ya-Nan Tian, Shiyan Ren(本科生), Jingwei Wang, Yi Xiao, Qiping Zhu* and Shiqing Li*, Palladium-catalysed dual ring-opening [3 + 4] annulation of isatoic anhydrides with cyclic iodoniums to build tribenzo[b,d,f]azepines and a mechanistic DFT study. Organic Chemistry Frontiers, 2022, 9, 6259-6264.  (一区，Link)

[18] Lingyu Huang,‡ Rongrong Xie,‡ Chaoying Wen, Yanyan Yang, Yiwen Wang, Shiyan Ren(本科生), Bin Huang(本科生) and Shiqing Li*. Decarbonylative/decarboxylative [4 + 2] annulation of phthalic anhydrides and cyclic iodoniums towards triphenylenes. Organic & Biomolecular Chemistry, 2022, 20, 3913–3916. (‡Equal contribution, Link) (Highlighted by Synfacts)

           

[17] Yuzhou Wang,‡ Yu Yu,‡ Rongrong Xie, Ya-Nan Tian, Lingyu Huang, Shihai Lv, Xiaona Meng(本科生), Xiangfei Kong and Shiqing Li*. Cu/Fe-mediated N(sp 2 )-arylation/alkenylation of pyridines with aryl-/alkenylboronic acids to yield versatile cationic materials. New Journal of Chemistry, 2022, 46, 2320–2325. (‡Equal contribution) (Link)

2021

[16] Yuzhou Wang, Rongrong Xie, Lingyu Huang, Ya-Nan Tian, Shihai Lv, Xiangfei Kong and Shiqing Li*. Divergent synthesis of unsymmetrical azobenzenes via Cu-catalyzed C–N coupling. Organic Chemistry Frontiers, 2021, 8, 5962–5967. (一区，Link)

[15] Xiangfei Kong, Ronggen Luo, Hongkang Gong, Dong Chen, Shijun Yang, Shiqing Li*, Guixia Wang*, and Zhiqun He*. Discotic liquid crystals with aggregation-induced emission properties based on tetraphenylethylene and triphenylene derivatives. Mol. Cryst. Liq. Cryst., 2021, 724, 26−37.

[14] Dong Chen, Shiqing Li, Jinhua Wang, Tiantian Gou, Linfeng Zhang, Guixia Wang*, and Xiangfei Kong*. Visible-light-mediated synthesis of rutaecarpine alkaloids through C–N cross-coupling reaction. Synlett, 2021, 32, 987−992.

2020

[13] Shiqing Li*, Hongxu Lv, Rongrong Xie, Xiuqing Ye(本科生) and Xiangfei Kong*. The C−H Activation/Bidirecting Group Strategy for Selective Direct Synthesis of Diverse 1,1′-Biisoquinolines. Organic Letters, 2020, 22, 4207−4212. (一区，Link)

[12] Rongrong Xie,# Hongxu Lv,# Xiuqing Ye(本科生), Xiangfei Kong* and Shiqing Li*. Cu-Catalyzed tandem N-arylation of phthalhydrazides with cyclic iodoniums to yield dihydrobenzo[c]cinnolines. Organic & Biomolecular Chemistry, 2020, 18, 4824−4830. (#Equal contribution) (Link)

[11] Yu Yu(本科生), Hongxu Lv and Shiqing Li*. The C–H functionalization of organic cations: an interesting and fresh journey. Organic & Biomolecular Chemistry, 2020, 18, 8810–8826. (Review, Link)

2019

[10] Shiqing Li*, Hongxu Lv, Yu Yu(本科生), Xiuqing Ye(本科生), Baisong Li(本科生), Songming Yang(本科生), Yanru Mo(本科生) and Xiangfei Kong*. Domino N-/C- or N-/N-/C-arylation of imidazoles to yield polyaryl imidazolium salts via atom-economical use of diaryliodonium salts. Chemical. Communications, 2019, 55, 11267−11270. (一区，Link)

---

2014-2018

[9]   Shiqing Li, Fan Yang, Taiyong Lv, Jingbo Lan, Ge Gao* and Jingsong You*, “Synthesis of unsymmetrical imidazolium salts by direct quaternization of N-substituted imidazoles using arylboronic acids”, Chem. Commun. 2014, 50, 3941−3943.

[8]   Shiqing Li, Junbin Tang, Yinsong Zhao, Ruyong Jiang, Tianbao Wang, Ge Gao* and Jingsong You*, “Cu-Catalyzed Controllable C−H Mono-/Di-/Triarylations of Imidazolium Salts for Ionic Functional Materials”, Chem. Commun. 2017, 53, 3489−3492.

[7]   Yinsong Zhao, Shiqing Li, Xuesong Zheng, Junbin Tang, Zhijie She, Ge Gao*, and Jingsong You*, “Rh/Cu-Catalyzed Cascade [4+2] Vinylic C−H O-Annulation and Ring Contraction of a-Aryl Enones with Alkynes in Air”, Angew. Chem. Int. Ed. 2017, 56, 4286−4289.

[6]   Junbin Tang, Shiqing Li, Zheng Liu, Yinsong Zhao, Zhijie She, Vilas D. Kadam, Ge Gao,* Jingbo Lan, and Jingsong You*，“Cascade C−H Annulation of Aldoximes with Alkynes Using O2 as the Sole Oxidant: One-Pot Access to Multisubstituted Protoberberine Skeletons”, Org. Lett. 2017, 19, 604-607.

[5]   Xiaoyu Li, Shiqing Li, Ge Gao, Di Wu, Jingbo Lan*, Ruiling Wang* and Jingsong You*，“High Performance Ruthenium Sensitizers Containing Imidazoliums as Counterions for the Efficient Dye-Sensitization in Water”, ChemSusChem. 2017, 10, 2914−29121.

[4]   Hongjun Zhou, Yinsong, Zhao, Ge Gao*, Shiqing Li, Jingbo Lan, and Jingsong You*, “Highly Selective Fluorescent Recognition of Sulfate in Water by Two Rigid Tetrakisimidazolium Macrocycles with Peripheral Chains”, J. Am. Chem. Soc. 2013, 135, 14908−14911.

[3]   Zhen He, Xiaotian Qi, Shiqing Li, Yinsong Zhao, Ge Gao*, Yu Lan*, Yiwei Wu, Jingbo Lan, and Jingsong You*, “Transition-Metal-Free Formal Decarboxylative Coupling of α-Oxocarboxylates with α-Bromoketones under Neutral Conditions: A Simple Access to 1,3-Diketones”, Angew. Chem. Int. Ed. 2015, 54, 855−859.

[2]   Yinsong Zhao, Zhen He, Shiqing Li, Junbin Tang, Ge Gao*, Jingbo Lan and Jingsong You*, “An Air-stable Half-sandwich RuII complex as an Rfficient Catalyst for [3+2] Annulation of 2-Arylcyclo-2-enones with Alkynes”, Chem. Commun. 2016, 52, 4613−4616.

[1]   Zhen He, Xiaotian Qi, Zhijie She, Yinsong Zhao, Shiqing Li, Junbin Tang, Ge Gao,* Yu Lan,* and Jingsong You*, “Room-Temperature Coupling/Decarboxylation Reaction of α‑Oxocarboxylates with α‑Bromoketones: Solvent-Controlled Regioselectivity for 1,2- and 1,3-Diketones”, J. Org. Chem. 2017, 82, 1403−1411.